This series contains memorandums and other documents relating to the review and maintenance of proposed research and demonstrations related to the use of human beings in health institutions as subjects in departmental projects. The Committee on Use of Human Beings in Research and Demonstration under the law must review each project, (1) to account for the rights and welfare of the participating individual, (2) to ascertain the appropriateness of methods used to secure informed consent, and (3) to make known the risks and potential medical benefits of the project. Included are: (1) the Committee's decision on the proposal; (2) Trial Form (7-66) to be filled out by the project director and enumerating points numbered one through three above; (3) narrative report describing the proposed project; (4) a sample questionnaire and consent form; (5) various memorandums clarifying procedures and rulings of the Committee.